Content

What is HEMANGEOL (propranolol hydrochloride oral solution)?

HEMANGEOL is a prescription medicine used to treat proliferating infantile hemangioma that requires treatment with a medicine that spreads throughout the body.

Important Safety Information for HEMANGEOL

Do not give HEMANGEOL to your child if your child:
  • was born prematurely and has not reached the corrected age of 5 weeks
  • weighs less than 4 ½ pounds
  • is allergic to propranolol or any of the other ingredients in HEMANGEOL
  • has asthma or a history of breathing problems
  • has a heart problem, slow heart rate (less than 80 heart beats per minute), very low blood pressure
  • is at risk for low blood sugar, for example is vomiting or unable to take feedings
  • has high blood pressure caused by a tumor on the adrenal gland, called “pheochromocytoma”

Tell the doctor about all medicines your child is taking, or all the medicines you are taking if you are breastfeeding.

HEMANGEOL can cause serious side effects, including:
Low blood sugar (hypoglycemia),
especially if your child is not taking feedings, or is vomiting. HEMANGEOL may make it more diifcult to recognize the signs and symptoms of low blood sugar in your child. To help reduce the risk of low blood sugar with HEMANGEOL, give HEMANGEOL during or shortly after feeding your child. Feed your child regulary during treatment. Tell your doctor if your child has a poor appetite. If your child is not taking feedings, due to an illness or vomiting, do not give HEMANGEOL until your child is taking feedings normally again.

If your child has any of the signs or symptoms of low blood sugar listed below during treatment with HEMANGEOL, stop giving your child HEMANGEOL and call your doctor or go to the nearest emergency room right away.

Signs or symptoms of low blood sugar include:
pale, blue or purple skin color, sweating, irritability, crying for no apparent reason, irregular or fast heartbeat, poor feeding, low body temperature, unusual sleepiness, seizures, breathing stops for short periods of time, and loss of consciousness

Other serious side effects can include:
  • New or worsening slow heart rate (bradycardia) or low blood pressure (hypotension).
  • Breathing problems or wheezing.
  • Stroke. HEMANGEOL may increase the risk of stroke in certain children who have severe problems with the blood vessels in their brain, particularly if your child has a large hemangioma that affects the face or head.
Call your doctor or go to the nearest hospital emergency room if your child has:
  • pale skin color, slow or uneven heartbeats, arms or legs feel cold, blue or purple skin color, or fainting.
  • breathing problems or wheezing during treatment with HEMANGEOL.

The most common side effects include: sleep problems, worsening respiratory tract infections, diarrhea, and vomiting.

These are not all the possible side effects of HEMANGEOL. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Medication Guide.

Centers of Excellence

There are more than 50 Centers of Excellence located throughout the United States. Centers of Excellence are medical centers that have shown an expertise in infantile hemangioma research. In addition to these centers, there are many local hospitals that may also have this expertise.

To find a Center of Excellence near you, use the map below or select your state from the drop-down menu.

Please note, this may not be a complete list. Please talk to your baby’s doctor to find out if there are additional centers near you.

 

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Ann & Robert H. Lurie Children’s Hospital of Chicago of Northwestern University
225 E Chicago Ave
Chicago, IL 60611
Phone: (312) 227-4000
Website: www.luriechildrens.org
University Of Illinois Hospital & Health Sciences System
1740 West Taylor Street
Chicago, IL 60612
Phone: (312) 996-7000
Website: hospital.uillinois.edu/
Riley Hospital For Children At IU Health North Hospital
11700 N. Meridian St.
Carmel, IN 46032
Phone: (317) 688-2000
Website: http://iuhealth.org
Indiana University – School of Medicine
340 W. 10th St., #6200
Indianapolis, IN 46202
Phone: (317) 688-2000
Website: http://medicine.iu.edu
The John Hopkins Hospital
1800 Orleans St.
Baltimore, MD 21287
Phone: (410) 955-5000
Website: www.hopkinschildrens.org
Children’s Hospital Colorado
13123 E. 16th. Ave
Aurora, CO 80045
Phone: 720-777-8445
Website: www.childrenscolorado.org/
Medstar Georgetown University Hospital
3800 Reservoir Rd., NW, 2nd Floor
Washington, DC 20007
Phone: 202-444-4972
Website: www.georgetownuniversityhospital.org/body_dept_home.cfm?id=607
Children’s National Medical Center
111 Michigan Ave, NW
Washington, DC 20010
Phone: 1-888-884-BEAR (2327)
Website: http://www.childrensnational.org/dermatology
Boston’s Children Hospital
300 Longwood Ave.
Boston, MA 02115
Phone: (617) 355-6000
Website: www.childrenshospital.org
Mercy Children’s Hospital St. Louis
615 S New Ballas Rd.
St Louis, MO 63141
Phone: (314) 251-6000
Website: www.mercy.net
St. Louis Children’s Hospital
1 Childeren’s Place
St. Louis, MO 63110
Phone: (314) 454-6000
Website: www.stlouischildrens.org
Children’s Mercy Hospitals & Clinics
2401 Gillham Rd.
Kansas City, MO 64108
Phone: (816) 234-3000
Website: www.childrensmercy.org
New York-Presbyterian Hospital, Columbia University Medical Center
3959 Broadway
New York, NY 10032
Phone: (212) 305-5437
Website: http://nyp.org
Vascular Birthmark Institute of New York
210 East 64th Street, 7th Floor
New York, NY 10065
Phone: (212) 434-4050
Website: www.vbiny.org
Mount Sinai Hospital
Faculty Practice/Pediatric Dermatology
5 East 98th Street, 5th Floor
New York, NY 10029
Phone: (212) 241-9728
Website: www.mountsinai.org
New York University Medical Center
550 First Avenue
New York, NY 10016
Phone: (212) 263-7300
Website: med.nyu.edu
Duke’s Children Hospital & Health Center
5324 McFarland Drive, Suite 410
Durham, NC 27707
Phone: (919) 684-3432 to schedule an appointment.
Office: (919) 401-7733
Website: www.dukechildrens.org
University of California, San Francisco
500 Parnassus Ave.
San Francisco, CA 94143
Phone: (415) 476-9000
Website: www.ucsfhealth.org
Vascular Birthmark Center of California
435 N. Bedford Drive
Beverly Hills, CA 901210
(610) 301-4522
Website: www.birthmarkcare.com
Dermatology Medical Group
500 Paseo Camarillo, Suite 104
Camarillo, CA 93010
Phone: (805) 482-4646
Website: www.dmgskincare.com
Dermatology Medical Group
2811 N Ventura Road
Oxnard, CA 93036
Phone: (805) 983-0343
Website: www.dmgskincare.com
Advanced Dermatology & Laser Center
255 Terracina Blvd.Suite 206
Redlands, CA 92373
Phone: (909)792-8600
Website: http://www.advanceddermatologylasercenter.com
UCLA Division of Dermatology
200 UCLA Medical Plaza
Los Angeles, CA 90095-6957
Phone: (310) 825-6911
Website: www.derm.med.ucla.edu
UCLA Santa Monica Dermatology
2020 Santa Monica Blvd. Suite 510
Santa Monica, CA 90404
Phone: (310) 917-3376
Website: www.derm.med.ucla.edu
Pediatric Dermatology of Orange County
3500 Barranca Pkwy #230
Irvine,, CA 92606
Phone: (949) 336-6569
Website: www.pedsdermoc.com
Wake Forest Baptist Medical Center
Medical Center Blvd.
Winston-Salem, NC 27157
Phone: (336) 716-2011
Website: www.wakehealth.edu
Children’s Hospital Cleveland Clinic
9500 Euclid Avenue
Cleveland, Ohio 44195
Phone: (216) 444-0261
Website: clevelandclinic.org
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229
Phone: (513) 636-4200
Website: www.cincinnatichildrens.org
Nationwide Children’s Hospital
700 Childrens Dr.
Columbus, OH 43205
Phone: (614) 722-2000
Website: www.nationwidechildrens.org
Children’s Hospital of Pittsburgh
4401 Penn Ave.
Pittsburgh, PA 15224
Phone: (412) 692-5325
Website: www.chp.edu
The Children’s Hospital of Philadelphia
3401 Civic Center Blvd.
Philadelphia, PA 19104
Phone: (215) 590-1000
Website: www.chop.edu
Rady’s Children Hospital of San Diego
3020 Children’s Way
San Diego, CA 92123
Phone: (858) 576-1700
Website: www.rchsd.org
Dell Children’s Medical Center of Central Texas
4900 Mueller Blvd.
Austin, TX 78723
Phone: (512) 324-0000
Website: www.dellchildrens.net
Baylor College of Medicine (located in Texas Medical Center)
1 Baylor Plaza
Houston, TX 77030
Phone: (713) 798-4951
Website: www.bcm.edu
Texas Dermatology and Laser Specialists
3320 Oakwell Farms
San Antonio, TX 78218
Phone: (210) 829-5180
Website: www.texasdls.com
Children’s Medical Center
1935 Medical District Dr.
Dallas, TX 75235
Phone: (214) 456-7000
Website: www.childrens.com
Plastic and Craniofacial Surgery for Infants and Children
7777 Forest Lane, Suite B-300
Dallas, TX 75230
Phone: (469) 375-3838
Website: www.kidsplastsurg.com
Texas Children’s Hospital
6621 Fannin St.
Houston, TX 77030
Phone: (832) 824-1000
Website: www.texaschildrens.org
Children’s Hospital of Richmond at Virginia Commonwealth University
2924 Brook Rd.
Richmond, VA 23220
Phone: (804) 228-5818
Website: www.childrenshosp-richmond.org
Children’s Hospital Los Angeles
4650 Sunset Blvd.
Los Angeles, CA 90027
Phone: (323) 660-2450
Website: www.chla.org
Children’s Hospital of Wisconsin
9000 W Wisconsin Ave.
Milwaukee, WI 53226
Phone: (414) 266-2000
Website: www.chw.org
Lenox Hill Hospital
100 E 77th St.
New York, NY 10065
Phone: (212) 434-2000
Website: www.lenoxhillhospital.org
Vascular Birthmark Center
200 W.57th St, Suite 1410
New York, NY 10019
Phone (212) 957-6933
Website: www.birthmarkcare.com
UC Irvine Medical Center
101 The City Drive South
Orange, CA, 92868
Phone: (714) 456-7890
Website: healthcare.uci.edu
Massachusetts Eye and Ear Infirmary
243 Charles St.
Boston, MA 02114
Phone: (617) 523-7900
Website: www.masseyeandear.org
Brigham and Women’s Hospital
45 Francis St.
Boston, MA 02115
Phone: (617) 525-6500
Website: www.brighamandwomens.org
Stanford School of Medicine
291 Campus Dr.
Stanford, CA 94305
Phone: (650) 725-3900
Website: med.stanford.edu
Yale Medical Group
300 George St.
New Haven, CT 06511
Phone: (203) 785-4851
Website: www.yalemedicalgroup.org
Miami Children’s Hospital
3100 SW 62nd Ave.
Miami, Florida 33155
Phone: (305) 669-6505
Website: www.mch.com
The Florida Center for Pediatric Dermatology
615 E. Princeton St, Suite 416
Orlando, FL 32803
Phone: 407-303-1687
Website: www.flpediatricdermatology.com
College of Medicine – University of Florida
1600 SW Archer Rd.
Gainesville, FL
Phone: (352) 273-7500
Website: med.ufl.edu
Children’s Hospital of Alabama
1600 7th Ave S.
Birmingham, AL 35233
Phone: (205) 638-9100
Website: www.childrensal.org
Arkansas Children’s Hospital
1 Children’s Way
Little Rock, AR 72202
Phone: (501) 364-1100
Website: www.archildrens.org
The Children’s Hospital in New Orleans
200 Henry Clay Ave.
New Orleans, LA 70118
Phone: (504) 899-9511
Website: www.chnola.org
Dartmouth-Hitchcock Children’s Hospital
One Medical Center Drive
Lebanon, NH 03756
Phone: (603) 653-9662
Website: chad.dartmouth-hitchcock.org
Women & Children’s Hospital of Buffalo
219 Bryant Street
Buffalo, NY 14222
Phone: (716) 878-7000
Website: www.kaleidahealth.org/childrens
Golisano Children’s Hospital – University of Rochester
601 Elmwood Ave.
Rochester, NY 14642
Phone: (585) 275-2821
Website: www.urmc.rochester.edu/childrens-hospital
Children’s Hospital of Oklahoma – Oklahoma University
1200 N. Children’s Ave
Oklahoma City, OK 73104
Phone: (405) 271-4700
Website: www.oumedicine.com/childrens
OHSU Doernbecher Children’s Hospital
700 SW Campus Dr.
Portland, OR 97239
Phone: (503) 494-8811
Website: www.ohsu.edu
Vanderbilt University Medical Center
1211 Medical Center Dr.
Nashville, Tennessee 37232
Phone: (615) 322-5000
Website: mc.vanderbilt.edu
Driscoll Children’s Hospital
3533 S. Alameda Street
Corpus Christi, Texas 78411
Phone: (361) 694-5000
Website: www.driscollchildrens.org
Children’s Hospital of the King’s Daughters
601 Childrens Lane
Norfolk, VA 23507
Phone: (757) 668-7000
Website: www.chkd.org
University of Virginia, School of Medicine
1215 Lee Street
Charlottesville, VA 22908
Phone: (434) 924-5118
Website: www.medicine.virginia.edu
Seattle Children’s Hospital
4800 Sand Point Way NE
Seattle, WA 98105
Phone: (206) 987-2000
Website: www.seattlechildrens.org
Mayo Clinic
200 First Street SW
Rochester, MN 55905
Phone: (507) 284-2511
Website: www.mayoclinic.com
Gillette Children’s Specialty Healthcare Hospital
435 Phalen Boulevard
St. Paul, MN 55130
Phone: (651) 291-2848
Website: www.gillettechildrens.org
RWJ University Hospital New Brunswick
One Robert Wood Johnson Place
New Brunswick, NJ 08901
Phone: (732) 828-3000 (main number)
VAMP Appointment: (732) 235-7816 ext. 3
Website: http://www.rwjuh.edu/vamp
The Pediatric Multidisciplinary Vascular Clinic
254 Easton Avenue
New Brunswick, NJ 08901
Phone: (732) 745 6674
Website: www.saintpetershcs.com
Goryeb Children’s Hospital at Morristown Medical Center
100 Madison Avenue, 2nd Floor
Morristown, NJ 07960
Phone: (973) 971 6720
Website: www.atlantichealth.org/goryeb/
Emory Clinic
1525 Clifton Road, NE
Atlanta, GA 30322
Phone: (404) 778-3333
Website: http://www.emoryhealthcare.org
Sanford Health
1305 W 18nd St.
Sioux Falls, SD 57117
Phone: (605) 333-1000
Website: www.sanfordhealth.org

What is HEMANGEOL (propranolol hydrochloride oral solution)?

HEMANGEOL is a prescription medicine used to treat proliferating infantile hemangioma that requires treatment with a medicine that spreads throughout the body.

Important Safety Information for HEMANGEOL

Do not give HEMANGEOL to your child if your child:
  • was born prematurely and has not reached the corrected age of 5 weeks
  • weighs less than 4 ½ pounds
  • is allergic to propranolol or any of the other ingredients in HEMANGEOL
  • has asthma or a history of breathing problems
  • has a heart problem, slow heart rate (less than 80 heart beats per minute), very low blood pressure
  • is at risk for low blood sugar, for example is vomiting or unable to take feedings
  • has high blood pressure caused by a tumor on the adrenal gland, called “pheochromocytoma”

Tell the doctor about all medicines your child is taking, or all the medicines you are taking if you are breastfeeding.

HEMANGEOL can cause serious side effects, including:
Low blood sugar (hypoglycemia),
especially if your child is not taking feedings, or is vomiting. HEMANGEOL may make it more diifcult to recognize the signs and symptoms of low blood sugar in your child. To help reduce the risk of low blood sugar with HEMANGEOL, give HEMANGEOL during or shortly after feeding your child. Feed your child regulary during treatment. Tell your doctor if your child has a poor appetite. If your child is not taking feedings, due to an illness or vomiting, do not give HEMANGEOL until your child is taking feedings normally again.

If your child has any of the signs or symptoms of low blood sugar listed below during treatment with HEMANGEOL, stop giving your child HEMANGEOL and call your doctor or go to the nearest emergency room right away.

Signs or symptoms of low blood sugar include:
pale, blue or purple skin color, sweating, irritability, crying for no apparent reason, irregular or fast heartbeat, poor feeding, low body temperature, unusual sleepiness, seizures, breathing stops for short periods of time, and loss of consciousness

Other serious side effects can include:
  • New or worsening slow heart rate (bradycardia) or low blood pressure (hypotension).
  • Breathing problems or wheezing.
  • Stroke. HEMANGEOL may increase the risk of stroke in certain children who have severe problems with the blood vessels in their brain, particularly if your child has a large hemangioma that affects the face or head.
Call your doctor or go to the nearest hospital emergency room if your child has:
  • pale skin color, slow or uneven heartbeats, arms or legs feel cold, blue or purple skin color, or fainting.
  • breathing problems or wheezing during treatment with HEMANGEOL.

The most common side effects include: sleep problems, worsening respiratory tract infections, diarrhea, and vomiting.

These are not all the possible side effects of HEMANGEOL. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Medication Guide.