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By using this website you agree to be bound and to abide by these Terms and Conditions of Use (“Terms”). Pierre Fabre Pharmaceuticals, Inc. (“we,” “us,” or “our”) reserve the right to amend these terms at any time and in any manner by posting the amended terms on this website. In addition to providing, reviewing, and understanding our website’s disclaimer, please check these terms periodically for changes. Your continued use of this website reaffirms your acceptance of, and your agreement to be bound and to abide by, these terms as amended. If you do not wish to be bound by these terms, you may not use this website.

Illegal use prohibited

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This website may include links to other websites. You enter linked websites at your own risk. Pierre Fabre Pharmaceuticals, Inc. is not responsible for the content of such websites or any link contained in a linked website and does not endorse any linked website. Pierre Fabre Pharmaceuticals, Inc. is not responsible or liable for any products, services, or content on or available from such websites. Pierre Fabre Pharmaceuticals, Inc. shall not be responsible or liable, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with use of or reliance on any such products, services, or content available on such external websites.

No warranties

You expressly agree that use of this website is at your own risk. Pierre Fabre Pharmaceuticals, Inc. expressly disclaims all warranties of any kind, whether expressed or implied, including, but not limited to, the implied warranties of merchantability, fitness for a particular purpose, and non-infringement. Pierre Fabre Pharmaceuticals, Inc. does not make any warranty as to the results that may be obtained from the use of the products, services, and information, or as to the accuracy or reliability of any products, services, and information obtained through this website. It is solely your responsibility to evaluate the quality and merchantability of all products, services, and information provided through this website.

Limitation of liability

Pierre Fabre Pharmaceuticals, Inc. shall not be liable for any direct, indirect, incidental, special, or consequential damages resulting from the use or inability to use this website or from the products, services, and information purchased or obtained through Pierre Fabre Pharmaceuticals, Inc., even if Pierre Fabre Pharmaceuticals, Inc. has been advised of the possibility of such damages.


This agreement shall be governed by and construed in accordance with the laws of the State of New Jersey without regard to any choice of law principles that could result in the application of the laws of any other jurisdiction. All actions relating to or in connection with this Agreement are to be venued in the state or federal courts of New Jersey.

Pierre Fabre Pharmaceuticals, Inc. shall not be liable for delays or failure to meet its obligations pursuant to this Agreement due to causes beyond the party’s reasonable control, provided the nonperforming party promptly notifies the other party of the nonperformance and takes all reasonable steps to recommence performance promptly.

If any provision of these terms is held to be invalid or unenforceable, the remainder of the provisions shall remain in full force and effect.

You agree that regardless of any statute or law to the contrary, any claim or cause of action arising out of or related to use of this website or these terms must be filed within one (1) year after such claim or cause of action arose. If you have any questions regarding these terms, please e-mail us at medinfo@pfpharmausa.com.

HEMANGEOL® (propranolol hydrochloride) oral solution is indicated for the treatment of proliferating infantile hemangioma requiring systemic therapy.

Important Safety Information


HEMANGEOL® (propranolol hydrochloride) oral solution is contraindicated in the following conditions:

  • Premature infants with corrected age < 5 weeks
  • Infants weighing less than 2 kg
  • Known hypersensitivity to propranolol or any of the excipients
  • Asthma or history of bronchospasm
  • Heart rate <80 beats per minute, greater than first degree heart block, or decompensated heart failure
  • Blood pressure <50/30 mmHg
  • Pheochromocytoma


HEMANGEOL prevents the response of endogenous catecholamines to correct hypoglycemia and masks the adrenergic warning signs of hypoglycemia, particularly tachycardia, palpitations and sweating. HEMANGEOL can cause hypoglycemia in children, especially when they are not feeding regularly or are vomiting; withhold the dose under these conditions. Hypoglycemia may present in the form of seizures, lethargy, or coma. If a child has clinical signs of hypoglycemia, parents should discontinue HEMANGEOL and call their health care provider immediately or take the child to the emergency room.

Concomitant treatment with corticosteroids may increase the risks of hypoglycemia.

HEMANGEOL may cause or worsen bradycardia or hypotension. Monitor heart rate and blood pressure after treatment initiation or increase in dose. Discontinue treatment if severe (<80 beats per minute) or symptomatic bradycardia or hypotension (systolic blood pressure <50 mmHg) occurs.

HEMANGEOL can cause bronchospasm; do not use in patients with asthma or a history of bronchospasm. Interrupt treatment in the event of a lower respiratory tract infection associated with dyspnea and wheezing.

HEMANGEOL may worsen circulatory function in patients with congestive heart failure or increase the risk of stroke in PHACE syndrome patients with severe cerebrovascular anomalies. Investigate infants with large facial infantile hemangioma for potential arteriopathy associated with PHACE syndrome prior to HEMANGEOL therapy.

HEMANGEOL will interfere with epinephrine used to treat serious anaphylaxis.


The most frequently reported adverse reactions to HEMANGEOL were sleep disorders, aggravated respiratory tract infections, diarrhea, and vomiting. Adverse reactions led to treatment discontinuation in fewer than 2% of treated patients.

Adverse events such as cardiac disorders, urticaria, alopecia, hypogylcemia, and bradycardia occurred in less than 1%.

Safety and effectiveness for infantile hemangioma have not been established in pediatric patients greater than 1 year of age.

Please see Full Prescribing Information and Medication Guide
Important Safety Information